For instance, circ_0008003 and exosomal circSATB2 were demonstrated to regulate zinc finger protein 281 (ZNF281) and fascin actin-bundling protein 1 (FSCN1), respectively, by sequestering miR-488 and miR-326, thereby promoting proliferation and metastasis of NSCLC cells [421, 422]. The gene discussed is ZNF281; the disease is non-small cell lung carcinoma.