Furthermore, constitutively activated EGFR-mutant cancer cells have been found to overexpress spalt-like Transcription factor 4 (SALL4)—a member of the zinc finger transcription factor which fuses with POU5F1, Sox2, and KLF4—resulting in the maintenance of CSC properties, including pluripotency gene expression and spheroid formation in NSCLC [380]. Here, EGFR is linked to non-small cell lung carcinoma.