TP53 and AIDS dementia complex: This study also identified genetic alterations, such as SMARCA4 (SWItch/Sucrose Nonfermentable, SWI/SNF related, Matrix associated, actin dependent regulator of chromatin, subfamily A, member 4) and TP53 mutations, linked to metastasis in primary ADC, noting that the risk associated with these alterations is disproportionately disseminated between organ sites [208].