SETDB1 and cancer: We note this narrower CNA segment does not include the MDM4 oncogene, which is located at 1q32.1, thus other genes must be driving this recurrent genetic change in CNA-PC86, with possible candidates being known cancer genes BCL9 (1q21.2), ARNT (1q21.3), SETDB1 (1q21.3), or SF3B4 (1q21.2).