Blatter et al. [40] investigated 11 polyps from carriers of a constitutional nonsense variant of BMPR1A (c.583 C > T, p.(Gln195*)) and found that the wild-type allele of BMPR1A was lost in 5/9 juvenile polyps (56%) but present in 2/2 adenomas. This evidence concerns the gene BMPR1A and adenoma.