LGALS3 and cancer: Several natural polysaccharides, glyco-peptides, and carbohydrate-compounds conjugates have been reported as galectin-3 inhibitors in the past few years and show to inhibit galectin-3-mediated actions in cancer (Marino et al. 2023; Duckworth et al. 2015; Ahmed and AlSadek 2015; Blanchard et al. 2014; Guha et al. 2013).