Both K55 and K57 retained the very low liver transduction from AAV-557-2, and in a panel of two ST88-14, one ipNF03.3 and one RHT92 tumor, AAV-K55-GFP showed remarkably higher transduction in NF1 tumors, compared to AAV9-GFP (Fig. 4F). Here, CCR4 is linked to neurofibromatosis type 1.