Comparison of LRRC15/Lrrc15 expression in cancer cells and stroma of HuO9 and U118MG tumors across clusters showed a trend of decreased expression with increasing cluster distance from untreated samples in both cancer cells and stroma (Fig. 6d); the expression of TGFB1, a known regulator of LRRC15 expression, mirrored the LRRC15/Lrrc15 expression pattern (Fig. 6d). Here, LRRC15 is linked to cancer.