G6PD and type 2 diabetes mellitus: Compared to QDiabetes-2018 score A, the inclusion of HbA1c in score C worsened the 10-year prediction of T2D as assessed by NRI, with a 75.0% reduction in true-positive rate [95% CI: 61.3, 88.7] in UK Biobank male G6PD carriers of Black ethnicity with T2D (Figure S7).