Experimental results revealed that the expression level of CEBPD and SOCS2 significantly increased in high-fat-induced liver cells and liver tissue of NFALD mice, indicating that CEBPD and SOCS2 may play a key role in both NAFLD and AIS and could serve as a potential diagnostic marker for AIS in NAFLD patients. This evidence concerns the gene SOCS2 and androgen insensitivity syndrome.