CHRNA4 and Lewy body dementia: Although we could derive a nAChR covariance pattern distinguishing DLB patients ‘on’ (n = 4) versus ‘off’ (n = 11) AChEI medication (F1,13 = 13.6, p = 0.003), bootstrap resampling revealed no individual voxels significantly contributed to this pattern with high confidence (|Z|≤ 1.64, p > 0.05), indicating an absence of regionally specific effects.