In a comprehensive 2023 analysis, Selvakumar reviewed multiple studies involving PCa patients and cell lines, concluding that the aberrant expression of miR-92a, miR-181a-5p, and miR-186-5p may contribute to PCa development through modulation of the PTEN/PI3K/AKT signaling pathway. This evidence concerns the gene AKT1 and posterior cortical atrophy.