CAT and colitis: Furthermore, DNBS-induced colitis caused a significant depletion of endogenous antioxidant defenses, as evidenced by reduced catalase activity (52.00 ± 16.57 mM/min/g of colon) and reduced GSH content (5.19 ± 1.54 μM/100 mg of protein compared with the non-colitic group (CAT: 156.21 ± 23.81; GSH: 18.16 ± 2.06; *** p< 0.001) (Figure 7C,D).