LncRNA-UCA1 has been reported to contribute to AML progression by upregulating the expression of CXCR4 (C-X-C Motif Chemokine Receptor 4) and CYP1B1 (Cytochrome P450 Family 1 Subfamily B Member 1), through binding and stabilization of the m6A methyltransferase METTL14. The gene discussed is METTL14; the disease is acute myeloid leukemia.