GSTM1 and chronic kidney disease: Post-transplant context: In renal transplant recipients, apply the same thresholds and velocity rules used in CKD anemia trials; in the randomized study of post-transplant anemia, ROX improved Hb and iron handling without excess infectious or thrombotic signals, supporting a standard Hb target of 10–12 g/dL with interruption above 12–13 g/dL as needed [58].