A subset of the highest-ranked predicted targets for repurposing include tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), tumor protein p53 (TP53), and AKT serine/threonine kinase 1 (AKT1); which could potentially be repurposed as protein targets for B-ALL (Table 4). This evidence concerns the gene TNF and precursor B-cell acute lymphoblastic leukemia.