The expression of markers such as FOXP3, CD274, LGALS1, CCL2, CCL5, IL2RA, LAG3, TNFRSF18, and HAVCR2 were upregulated in the AML group, indicating that immune modulation processes were activated, potentially influencing T cell activation, differentiation, migration, and checkpoint signaling, and thereby reshaping the immune landscape within the leukemic microenvironment (Figure 7B). The gene discussed is CCL5; the disease is acute myeloid leukemia.