Zinc Finger E‐box Binding Homeobox 1 (ZEB1) and zinc fingers and homeoboxes 3 (ZHX3) have been extensively implicated in promoting epithelial‐mesenchymal transition (EMT), enhancing tumor cell migration and invasion, and thereby contributing to cancer aggressiveness and poor prognosis [15, 16, 17, 18]. This evidence concerns the gene ZHX3 and cancer.