Furthermore, lipoproteins (i.e., complexes of proteins and lipids) have gained attention as potential biomarkers in CRC; Xu et al. reported that decreased levels of lipoproteins were associated with CRC, yielding 85.7% sensitivity and 93.3% specificity when investigating differences in levels of apolipoprotein A2 between cancerous and healthy patients. The gene discussed is APOA2; the disease is colorectal carcinoma.