BECN1 and Alzheimer disease: al. have evaluated the effect of extra virgin olive oil polyphenols, namely a mixture of Oleuropein aglycone and hydroxytyrosol in Alzheimer's Disease and have consequently observed reduced levels of autophagy suppressive markers in SH‐SY5Y neuroblastoma cell lines such as ribosomal protein S6 and p62 and elevated levels of phagocytotic markers like Beclin‐1, LC3‐II/LC3‐I ratio [47].