MKI67 and neoplasm: Ki-67 also showed notable associations with lesion location and imaging characteristics: higher values were observed in Gasserian ganglion metastases and hemorrhagic lesions, while lower values characterized occipital lobe lesions and solitary metastases, paralleling recent neuropathological studies linking tumor microenvironment and vascular fragility to proliferation rates and hemorrhagic propensity [27].