VAV1 and acute lymphoblastic leukemia: Clinically relevant polymorphisms include the Vav1 R63W variant, which predisposes to myasthenia gravis through enhanced IFN‐γ/IL‐17A production [267], while Vav3 exhibits noncanonical nuclear functions in B‐cell acute lymphoblastic leukemia (B‐ALL) by sustaining epigenetic silencing through PRC1 complex interactions [268].