Since NR4A2 plays a role in maintenance of adult midbrain dopaminergic neuron, it is also associated with neurodegenerative diseases, such as Parkinson’s or Alzheimer’s disease, schizophrenia, and manic depression (Le et al., 2003; Buervenich et al., 2000). The gene discussed is NR4A2; the disease is schizophrenia.