CD274 and glioblastoma: Further exploring the applications of [18F]AlF-NOTA-PCP2, another study by Wang et al. evaluated its efficacy in visualizing PD-L1-driven radioresistance in glioblastoma.18 The tracer not only quantified the spatial heterogeneity of PD-L1-expressing cells but also showed increased uptake postradiotherapy in PD-L1-positive tumors, aligning with observed radioresistance.