Advancing the development of novel imaging agents, Wang et al. introduced a peptide-based PET tracer, [18F]AlF-NOTA-PCP2, designed to enhance the imaging of PD-L1 heterogeneity in glioblastoma xenografts.19 The tracer was synthesized with high radiochemical purity and demonstrated strong and specific affinity for PD-L1, comparable to the established tracer [18F]AlF-NOTA-WL12. This evidence concerns the gene CD274 and glioblastoma.