These associations were statistically mediated by IL-6 (12 % (p-valueFDR = 0.012) of the association with CVD, 17 % T2DM (p-valueFDR<0.001), 18 % hypertension (p-valueFDR<0.001), and 29 % obesity (p-valueFDR = 0.005)). The gene discussed is IL6; the disease is type 2 diabetes mellitus.