It upregulated SREBP‐1a, SREBP‐1c, SREBP‐2, VEGF, TGF‐β1, and PPAR‐α expression in DKD experimental animals, resulting in the amelioration of abnormal glucose and lipid metabolism and thus alleviating the progression of renal fibrosis (Hu et al. 2021). The gene discussed is SREBF1; the disease is diabetic kidney disease.