Others include modulating enzymes like lipoprotein lipase, glucose‐6‐phosphatase, lactate dehydrogenase, and aldose reductase; and improvement of hyperlipidemia, renal function, and other diabetic complications (Dewanjee et al. 2020; Pereira et al. 2019; Unuofin and Lebelo 2020). The gene discussed is AKR1B1; the disease is hyperlipidemia.