CTLA4 and arthritic joint disease: Kaplan–Meier curves of arthritisincidence (score >0), low disease score (score >0.5) and highdiseasescore (score >1) showed that all untreated mice achieved a scoregreaterthan 0 by day 3, all human IgG and CTLA-4 IgG mice achieved a scoregreater than 0 by day 7, and one mouse did not develop arthritis inthe CTLA-4 IgG+Agg-CLNP group (Figure d).