TRNT1 and congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome: As more atypical or mild SIFD cases are identified worldwide, it is increasingly recognized that alterations in TRNT1 expression/function may be associated with more heterogenous pathologies and increased susceptibilities to bacterial and viral infections such as Staphylococcus, cytomegalovirus, & COVID-19 (5, 65–70).