FN1 and colorectal carcinoma: Fn abundance tends to increase with CRC stage and is more prevalent in right-sided tumors, which are often characterized by microsatellite instability-high/mismatch repair deficient (MSI/dMMR), CpG island methylator phenotype (CIMP), and BRAF (11–16) mutations, suggesting a crucial role of Fn in the development and progression of CRC (17).