Although the detailed pathological mechanisms of PI-IBS are unknown, recent studies have shown changes in the AhR/IL-22 pathway within preclinical models of PI-IBS.Research has found that Lactobacillus rhamnosus GG (LGG) can effectively prevent porcine epidemic diarrhea virus (PEDV) infection in piglets. This evidence concerns the gene AHR and irritable bowel syndrome.