Other factors did not significantly affect OS, including tumour size (p=0.626), lymph node involvement (p=0.495), histological subtype (p=0.512), menopausal status (p=0.107), SBR histoprognostic grade (p=0.673), hormone receptor status (p=0.07), extraspinal bone metastasis (p=0.296), visceral metastases (p=0.087), and vascular emboli (p=0.83). This evidence concerns the gene NR4A1 and bone metastasis.