KLK3 and metastatic malignant neoplasm in the lymph nodes: Demographic and clinical data were manually extracted from institutional medical records, including age, PSA level at diagnosis, Gleason score, presence of visceral and lymph node metastases, extent of disease (EOD) score, number of prior DTX cycles, time to progression to CRPC, sequence of DR, PSA level at DR initiation, time to progression, follow-up duration, and oncological outcomes.