POSTN and hepatocellular carcinoma: The POSTN-integrin signaling axis has garnered attention due to its involvement in several processes critical for HCC progression, including epithelial-mesenchymal transition (EMT), angiogenesis, and the establishment of a pro-tumorigenic microenvironment (Xiao et al., 2021; Chen B. C. et al., 2020; Chen et al., 2017).