In addition to CBD, other underlying pathologies such as progressive supranuclear palsy, Alzheimer’s disease (AD), TDP-43 proteinopathy, fused in sarcoma (FUS) proteinopathy, prion disease, cerebrovascular pathology, and in rare instances even synucleinopathies have been reported (21). This evidence concerns the gene FUS and early-onset autosomal dominant Alzheimer disease.