Results showed that, when this stratification of the cohort was applied, a stepwise increase of infiltration by TILs, TAMs, CD8+ T cells, and CD68+ macrophages from DCIS via IDC-EIC to IDC-RIC was observed (AKW p < 0.0001; Figures 1, 2A, B, Supplementary Table 3, Supplementary Figure 2). This evidence concerns the gene CD8A and ductal breast carcinoma in situ.