CRP, a well-established acute-phase reactant, showed strong diagnostic utility with significantly higher levels in pneumonia cases (median: 28.3 mg/L, IQR: 4.3–51.9) vs. controls (median: 2.0 mg/L, IQR: 1.7–2.5; p < 0.001), confirming its established role as a sensitive marker for pneumonia diagnosis (16). This evidence concerns the gene CRP and pneumonia.