CLEC7A and infection: Specifically, the activation of the Dectin-1-Syk signaling axis via β-glucan induces H3K4me3 modification in monocytes and up-regulates the expression of inflammatory vesicle genes, thereby enhancing antifungal activity during secondary infection (Arts et al., 2016; Bekkering et al., 2021; Eastman et al., 2019; Geckin et al., 2022; Netea et al., 2016).