It has been reported that persistently phosphorylated or overexpressed SRC kinase leads to pathological modulation of several tumor cells proliferation-relevant signaling, namely PI3K/AKT pathway, MEK/ERK pathway, and JAK/STAT3 pathway (Ferguson et al., 2013; Rodriguez Torres et al., 2023; Xu R. et al., 2023). This evidence concerns the gene AKT1 and neoplasm.