After treatment of CRC cells with exosomes mediating circTAX1BP1 knockdown (CRCsi‐circTAX1BP1‐Evs), SP1 and TGF‐β expression levels and CM concentration of TGF‐β in HCT116 and DLD1 cells were markedly decreased (Figure 6H,I; Figure S11A, Supporting Information). Here, TGFB1 is linked to colorectal carcinoma.