SP1 and cancer: As an m6A transferase, VIRMA, similar to METTL3/METTL14/WTAP, promotes the m6A modification of target RNA and increases or decreases its stability.[53] Although the known target RNAs of VIRMA are limited, its cancer‐promoting function has been reported in various malignant tumors.[54, 55, 56] In this study, using RNA‐seq and MeRIP, we confirmed that the downstream target mRNA of lactylation VIRMA is SP1.