Notably, certain single nucleotide polymorphisms (SNPs) that are present in m1A writers (TRMT6), erasers (FTO), and readers (YTHDC1 and YTHDF2) have been associated with the risk of Wilms tumour risk [20, 21, 22, 23], emphasising the significant role of m1A modification regulators in Wilms tumour development. The gene discussed is YTHDF2; the disease is Wilms tumor.