Further subcellular fractionation and immunofluorescence staining showed that in NSCLC cells, the protein levels of WT1 in both the nucleus and cytoplasm were up-regulated when SNRPG was knocked down.WT1 is known to shuttle between the nucleus and cytoplasm, and its different isoforms are involved in various aspects of gene expression regulation, including transcription and RNA processing [50–52]. This evidence concerns the gene SNRPG and non-small cell lung carcinoma.