While Chen et al. found that WT1 inhibited E-cadherin expression in NSCLC cells, thereby enhancing their invasive and migratory capabilities, and Xu et al. reported that WT1 promoted NSCLC cell proliferation by upregulating Cyclin D1 and p-pRb expression [48, 49]. This evidence concerns the gene RB1 and non-small cell lung carcinoma.