Among these 10 subgroups of epithelial cells, cancer cells_CDK1 were characterized by high expression of UBE2C, CDK1, TOP2A, PLK1, NEK2, NDC80, KIF20A, DLGAP5, CDC20, and CCNA2 (Fig. 4c), indicating high cell cycle activity. The gene discussed is PLK1; the disease is cancer.