Recently, increasing attention has been given to RHBDL4 regulation by various microRNAs (miRNAs) in cancer (Zhao et al. 2019; Niu et al. 2019; Chen, Cai et al. 2022; Wang et al. 2023; Wang et al. 2020; Koni et al. 2020; Wei et al. 2022; Roshani et al. 2023). This evidence concerns the gene RHBDD1 and cancer.