This enlarged scar burden directly correlates with clinical outcomes, as demonstrated by MRI studies showing that extensive scarring independently predicts mortality, heart failure progression, and arrhythmic risk.[55, 56, 57] Advanced imaging techniques reveal how transmural scar extent correlates with sudden cardiac death[57, 58, 59, 60], while our model demonstrates that ADAMTS1‐mediated expansion replaces viable myocardium and disrupts electrical conduction pathways.[61] Simultaneously, ADAMTS1 disrupts the natural temporal progression of scar mechanical maturation. The gene discussed is ADAMTS1; the disease is heart failure.