CRP and major depressive disorder: The voxel‐wise correlation analysis revealed that CRP was positively correlated with fALFF of the right precentral gyrus (PreCG, cluster size = 29 voxels, peak MNI coordinate x/y/z = 18/−24/66, peak t = 4.640), and negatively correlated with fALFF of the bilateral anterior cingulate cortex (ACC, cluster size = 28 voxels, peak MNI coordinate x/y/z = 3/36/6, peak t = −4.240) and bilateral middle cingulate cortex (MCC, cluster size = 27 voxels, peak MNI coordinate x/y/z = −3/−9/27, peak t = −4.498) in MDD patients (cluster‐level p < 0.05, FWE corrected) (Figure 2A).