SCO1 and systemic lupus erythematosus: The final model included 9 bacterial genes (sco1, lldG, cysK, ABC.CD.P, pimC, ABCB-BAC, selA, transposase, ABC.CD.A) and achieved an AUC score of 0.7 (accuracy: 0.87, precision: 0.78) for distinguishing renal SLE patients from non-renal SLE patients and heathy controls (Fig. 3c).