IFNG and colitis: Regarding the biological effects of these nanoparticles in mice with colitis (by DSS oral administration), attenuation of body weight loss and restoration of colon length were observed, as well as reduced production of IFN-γ and IL-6, improved IL-10, and increased production of short-chain fatty acids, such as acetate, propionate, and butyrate, in the colon with colitis.