Zhong et al. summarized advances in polymer-based nano-delivery systems for the encapsulation of anthocyanin and reported that such systems not only markedly improve the solubility and bioavailability of anthocyanins but also exert robust anti-inflammatory effects in multiple IBD models through targeted regulation of NF-κB signaling pathways, modulation of the gut microbiota, and suppression of oxidative stress [30]. The gene discussed is NFKB1; the disease is inflammatory bowel disease.