Another Ap-NP example resides on the DNA aptamer conjugate with cisplatin AptBCis1 that crosses the BBB and binds to NCL, Na+-dependent excitatory amino acid transporters or solute carrier family 1 member 2 EAAT2/SLC1A2, and human Y-box binding protein 1 YB-1 proteins, which are overexpressed on lung cancer leptomeningeal carcinomatosis (LM). This evidence concerns the gene SLC1A2 and lung cancer.