Influenza-induced cytokine storms commonly involve proinflammatory mediators (TNF-α, IFN-γ, IL-1β, IL-2, IL-6, CXCL8, CCL2, CCL3, CXCL10, G-CSF, FGF, VEGF) and anti-inflammatory factors (TGF-β, IL-10, IL-1RA) [168,209]. The gene discussed is TNF; the disease is influenza.