The defining molecular event in BL is the juxtaposition of the myc oncogene to the immunoglobulin gene heavy chain (IGH) locus t(8, 14)(q24; q32) and less commonly to the IG lambda (IGL) or kappa (IGK) locus t(8, 22)(q24; q11) or t(2, 8)(p12; q24). Here, MYC is linked to Burkitt lymphoma.