In these situations, screening for anti-HDV may be performed only in specific subsets of HBsAg-positive individuals, such as those born and living in HDV-endemic areas; patients with advanced hepatic disease, undergoing hepatitis B therapy who exhibit features suggestive of HDV infection, such as low HBV DNA alongside high alanine aminotransferase (ALT) levels; populations at higher risk for HDV infection, including hemodialysis recipients; people coinfected with hepatitis C virus or HIV; sex workers; PWID; and men who have sex with men [19]. Here, GPT is linked to hepatitis B virus infection.